MY FIANCE LACKS AN ENZYME IN HIS LIVER TO PROCESS ALCOHOL. WHAT IS THIS DISORDER CALLED?Ok... So my fiance has some kind of liver disorder that causes him to not be able to drink alcohol. He was told he lacks an enzyme in his liver to process the alcohol. He will get very sick if he consumes any alcohol at all. (throws up blood, severe pains, etc). what is this disorder called and what are the causes? also, is it genetic and are there any treatments ?
Posted by Peniqua
alcohol-illtolerance.
Posted by Erin J
LIkely alcohol dehydrogenase deficiency. It does have a genetic component and is very common is Asian populations. The treatment is to avoid alcohol.
Posted by Sach
More likely to be Acetaldehyde dehydrogenase deficiency than Alcohol dehydrogenase deficiency... because if a person has Aldehyde dehydrogenase deficiency, then Acetaldehyde accumulates in the body, which is toxic, and causes the symptoms that your fiance is experiencing.
Alcohol flush reaction, or Asian flush reaction (what the previous commenter mentioned) is because of Acetaldehyde dehydrogenase deficiency, NOT Alcohol dehydrogenase deficiency.
After a person drinks alcohol, it gets broken down into Acetaldehyde first by Alcohol dehydrogenase, then into harmless Acetic Acid by Acetaldehyde dehydrogenase, and Acetic acid finally gets eliminated by conversion to carbon dioxide and water.
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